UPDATE 9:15 p.m.: York Police Department has declared that the affected area of Route 1 has been re-opened.

UPDATE: Route 1 northbound remains closed, but southbound is back open. There are no life-threatening injuries from the crash.

YORK, Maine (NEWS CENTER) -- Route 1 and Spur Road in York are closed in both directions due to a crash involving 10 vehicles.

A tractor-trailer overturned Thursday evening on Route 1, shutting down the on/off ramps at exit 7 on I-95. The Spur Road intersection is also closed.